STARDdem

The Cochrane Dementia and Cognitive Improvement Group (CDCIG) set up and co-ordinated an initiative to review the current standard of reporting in diagnostic test accuracy studies in dementia and cognitive impairment, and to generate, through a consensus process, enhanced guidance to the STARD checklist: the STARDdem Initiative.

The STARD Statement was published in 2003 by Patrick Bossuyt and colleagues and can be accessed at www.stard-statement.org.

The STARDdem initiative comprised three broad phases:

Phase 1: Evaluation of existing studies through a systematic literature review. This has now been published:

Noel-Storr AH, Flicker L, Ritchie CW, Nguyen GH, Gupta T, Wood P, Walton J, Desai M, Fraser Solomon D, Molena E, Worrall R, Hayen A, Choudhary P, Ladds E, Lanctot KL, Verhey FR, McCleery JM, Mead G, Clare L, Fiorivanti M, Hyde C, Marcus S, McShane R. Systematic review of the body of evidence for use of biomarkers in the diagnosis of dementia. Alzheimer’s & Dementia 2013; 9: e96-e105

The review of dementia studies published in 2013 found that many studies failed to report on key areas.

Phase 2: Formation of a Working Group who drafted initial supplementary guidance using a modified Delphi technique. The draft guidance was sent to over 350 experts. Feedback was collated and incorporated and presented at a consensus meeting.

The following documents can be accessed and downloaded below:

First draft of supplementary guidance

Comments received during wider participation round

Phase 3: Publication and further dissemination of the supplementary guidance - in process. Once published a print version of the STARD checklist with additional dementia-specific guidance will be available for downloading and printing.

It is hoped that the final version of the STARDdem guidance will be published by early 2014.

If you have any questions or want to find out a bit more about this initiative please do get in touch: anna.noel-storr@rdm.ox.ac.uk

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